Expression profiling of blood samples from an SU5416 Phase III metastatic colorectal cancer clinical trial: a novel strategy for biomarker identification

Abstract Background Microarray-based gene expression profiling is a powerful approach for the identification of molecular biomarkers of disease, particularly in human cancers.Utility of this approach to s2720 measure responses to therapy is less well established, in part due to challenges in obtaining serial biopsies.Identification of suitable surr

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